increased glucagon secretion_Wfs1<tm1Yoka>/Wfs1<tm1Yoka>

http://metadb.riken.jp/0002710I129SvC57BL6Wfs1tm1YokaWfs1tm1YokaWfs1tm1Yoka

increased glucagon secretion_Wfs1<tm1Yoka>/Wfs1<tm1Yoka>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• wolframin ER transmembrane glycoprotein
  http://metadb.riken.jp/db/mgi_rdf/MGI:1328355

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Wfs1<tm1Yoka>/Wfs1<tm1Yoka>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Wfs1<tm1Yoka>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased glucagon secretion
  http://purl.obolibrary.org/obo/MP_0002710

文献

http://purl.org/net/cito/citesAsAuthority

• Hisamitsu. Ishihara, et.al., Disruption of the WFS1 gene in mice causes progressive beta-cell loss and impaired stimulus-secretion coupling in insulin secretion., Human molecular genetics, 2004, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/15056606