increased circulating glucagon level_Gnas<tm5Lsw>/Gnas<tm5Lsw>,Tg(Alb1-cre)1Dlr/?

http://metadb.riken.jp/0002712I129S6SvEvTacBlackSwissFVBNGnastm5LswGnastm5LswTgAlb1cre1DlrGnastm5LswTgAlb1cre1Dlr

increased circulating glucagon level_Gnas<tm5Lsw>/Gnas<tm5Lsw>,Tg(Alb1-cre)1Dlr/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
  http://metadb.riken.jp/db/mgi_rdf/MGI:95777
• transgene insertion 1, Derek LeRoith
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176944

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gnas<tm5Lsw>/Gnas<tm5Lsw>,Tg(Alb1-cre)1Dlr/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gnas<tm5Lsw>|Tg(Alb1-cre)1Dlr

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * Black Swiss * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating glucagon level
  http://purl.obolibrary.org/obo/MP_0002712

文献

http://purl.org/net/cito/citesAsAuthority

• Min. Chen, et.al., Increased glucose tolerance and reduced adiposity in the absence of fasting hypoglycemia in mice with liver-specific Gs alpha deficiency., The Journal of clinical investigation, 2005, 115
  http://rdf.ncbi.nlm.nih.gov/pubmed/16239968