decreased circulating insulin level_Hsd11b1<tm1Ggla>/Hsd11b1<tm1Ggla>,Tg(Alb-cre)21Mgn/0

http://metadb.riken.jp/0002727I129P2OlaHsdC57BL6DBAHsd11b1tm1GglaHsd11b1tm1GglaTgAlbcre21Mgn0TgAlbcre21MgnHsd11b1tm1Ggla

decreased circulating insulin level_Hsd11b1<tm1Ggla>/Hsd11b1<tm1Ggla>,Tg(Alb-cre)21Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• hydroxysteroid 11-beta dehydrogenase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:103562
• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hsd11b1<tm1Ggla>/Hsd11b1<tm1Ggla>,Tg(Alb-cre)21Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Alb-cre)21Mgn|Hsd11b1<tm1Ggla>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased circulating insulin level
  http://purl.obolibrary.org/obo/MP_0002727

文献

http://purl.org/net/cito/citesAsAuthority

• Gareth G. Lavery, et.al., Lack of significant metabolic abnormalities in mice with liver-specific disruption of 11β-hydroxysteroid dehydrogenase type 1., Endocrinology, 2012, 153
  http://rdf.ncbi.nlm.nih.gov/pubmed/22555437