decreased circulating insulin level_Chrm3<tm1Jwe>/Chrm3<tm1Jwe>

http://metadb.riken.jp/0002727I129S6SvEvTacC57BL6JChrm3tm1JweChrm3tm1JweChrm3tm1Jwe

decreased circulating insulin level_Chrm3<tm1Jwe>/Chrm3<tm1Jwe>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cholinergic receptor, muscarinic 3, cardiac
  http://metadb.riken.jp/db/mgi_rdf/MGI:88398

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Chrm3<tm1Jwe>/Chrm3<tm1Jwe>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Chrm3<tm1Jwe>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased circulating insulin level
  http://purl.obolibrary.org/obo/MP_0002727

文献

http://purl.org/net/cito/citesAsAuthority

• Alokesh. Duttaroy, et.al., Muscarinic stimulation of pancreatic insulin and glucagon release is abolished in m3 muscarinic acetylcholine receptor-deficient mice., Diabetes, 2004, 53
  http://rdf.ncbi.nlm.nih.gov/pubmed/15220195
• M. Yamada, et.al., Mice lacking the M3 muscarinic acetylcholine receptor are hypophagic and lean., Nature, 2001, 410
  http://rdf.ncbi.nlm.nih.gov/pubmed/11242080