decreased circulating insulin level_Hnf1a<tm1.1Ylee>/Hnf1a<tm2Ylee>,Tg(Alb-cre)21Mgn/?

http://metadb.riken.jp/0002727I129X1SvJC57BL6DBAHnf1atm11YleeHnf1atm2YleeTgAlbcre21MgnHnf1atm2YleeTgAlbcre21MgnHnf1atm11Ylee

decreased circulating insulin level_Hnf1a<tm1.1Ylee>/Hnf1a<tm2Ylee>,Tg(Alb-cre)21Mgn/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• HNF1 homeobox A
  http://metadb.riken.jp/db/mgi_rdf/MGI:98504
• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hnf1a<tm1.1Ylee>/Hnf1a<tm2Ylee>,Tg(Alb-cre)21Mgn/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Hnf1a<tm2Ylee>|Tg(Alb-cre)21Mgn|Hnf1a<tm1.1Ylee>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased circulating insulin level
  http://purl.obolibrary.org/obo/MP_0002727

文献

http://purl.org/net/cito/citesAsAuthority

• Ying-Hue. Lee, et.al., Liver-specific reactivation of the inactivated Hnf-1alpha gene: elimination of liver dysfunction to establish a mouse MODY3 model., Molecular and cellular biology, 2003, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/12529398