abnormal semilunar valve morphology_Hey2<tm1Kkb>/Hey2<tm1Kkb>

http://metadb.riken.jp/0002746I129S7SvEvBrdC57BL6Hey2tm1KkbHey2tm1KkbHey2tm1Kkb

abnormal semilunar valve morphology_Hey2<tm1Kkb>/Hey2<tm1Kkb>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• hairy/enhancer-of-split related with YRPW motif 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1341884

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hey2<tm1Kkb>/Hey2<tm1Kkb>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Hey2<tm1Kkb>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal semilunar valve morphology
  http://purl.obolibrary.org/obo/MP_0002746

文献

http://purl.org/net/cito/citesAsAuthority

• Hiroki. Kokubo, et.al., Hesr2 knockout mice develop aortic valve disease with advancing age., Arteriosclerosis, thrombosis, and vascular biology, 2013, 33
  http://rdf.ncbi.nlm.nih.gov/pubmed/23288164
• Hiroki. Kokubo, et.al., Targeted disruption of hesr2 results in atrioventricular valve anomalies that lead to heart dysfunction., Circulation research, 2004, 95
  http://rdf.ncbi.nlm.nih.gov/pubmed/15297376