increased circulating testosterone level_Cyp19a1<tm1Toda>/Cyp19a1<tm1Toda>

http://metadb.riken.jp/0002781I129P2OlaHsdC57BL6JCyp19a1tm1TodaCyp19a1tm1TodaCyp19a1tm1Toda

increased circulating testosterone level_Cyp19a1<tm1Toda>/Cyp19a1<tm1Toda>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cytochrome P450, family 19, subfamily a, polypeptide 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88587

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cyp19a1<tm1Toda>/Cyp19a1<tm1Toda>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cyp19a1<tm1Toda>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating testosterone level
  http://purl.obolibrary.org/obo/MP_0002781

文献

http://purl.org/net/cito/citesAsAuthority

• K. Toda, et.al., Oestrogen at the neonatal stage is critical for the reproductive ability of male mice as revealed by supplementation with 17beta-oestradiol to aromatase gene (Cyp19) knockout mice., The Journal of endocrinology, 2001, 168
  http://rdf.ncbi.nlm.nih.gov/pubmed/11241177
• K. Toda, et.al., Targeted disruption of the aromatase P450 gene (Cyp19) in mice and their ovarian and uterine responses to 17beta-oestradiol., The Journal of endocrinology, 2001, 170
  http://rdf.ncbi.nlm.nih.gov/pubmed/11431142
• C. Miyaura, et.al., Sex- and age-related response to aromatase deficiency in bone., Biochemical and biophysical research communications, 2001, 280
  http://rdf.ncbi.nlm.nih.gov/pubmed/11162635
• K. Takeda, et.al., Progressive development of insulin resistance phenotype in male mice with complete aromatase (CYP19) deficiency., The Journal of endocrinology, 2003, 176
  http://rdf.ncbi.nlm.nih.gov/pubmed/12553872