impaired skin barrier function_Plec<tm4Gwi>/Plec<tm4Gwi>,Tg(KRT5-cre)1Tak/?

http://metadb.riken.jp/0002796I129P2OlaHsdC3HC57BL6Plectm4GwiPlectm4GwiTgKRT5cre1TakPlectm4GwiTgKRT5cre1Tak

impaired skin barrier function_Plec<tm4Gwi>/Plec<tm4Gwi>,Tg(KRT5-cre)1Tak/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Junji Takeda
  http://metadb.riken.jp/db/mgi_rdf/MGI:1926776
• plectin
  http://metadb.riken.jp/db/mgi_rdf/MGI:1277961

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Plec<tm4Gwi>/Plec<tm4Gwi>,Tg(KRT5-cre)1Tak/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Plec<tm4Gwi>|Tg(KRT5-cre)1Tak

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C3H * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired skin barrier function
  http://purl.obolibrary.org/obo/MP_0002796

文献

http://purl.org/net/cito/citesAsAuthority

• Reinhard. Ackerl, et.al., Conditional targeting of plectin in prenatal and adult mouse stratified epithelia causes keratinocyte fragility and lesional epidermal barrier defects., Journal of cell science, 2007, 120
  http://rdf.ncbi.nlm.nih.gov/pubmed/17606998