impaired skin barrier function_Cyp27b1<tm1Star>/Cyp27b1<tm1Star>

http://metadb.riken.jp/0002796I129S1Sv129X1SvJC57BL6Cyp27b1tm1StarCyp27b1tm1StarCyp27b1tm1Star

impaired skin barrier function_Cyp27b1<tm1Star>/Cyp27b1<tm1Star>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cytochrome P450, family 27, subfamily b, polypeptide 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1098274

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cyp27b1<tm1Star>/Cyp27b1<tm1Star>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cyp27b1<tm1Star>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired skin barrier function
  http://purl.obolibrary.org/obo/MP_0002796

文献

http://purl.org/net/cito/citesAsAuthority

• D D. Bikle, et.al., 25 Hydroxyvitamin D 1 alpha-hydroxylase is required for optimal epidermal differentiation and permeability barrier homeostasis., The Journal of investigative dermatology, 2004, 122
  http://rdf.ncbi.nlm.nih.gov/pubmed/15102089