impaired skin barrier function_Esrp1<tm1.1Rpc>/Esrp1<tm1.1Rpc>,Esrp2<tm1(KOMP)Vlcg>/Esrp2<tm1(KOMP)Vlcg>,Tg(KRT14-cre)43Smr/0

http://metadb.riken.jp/0002796I129S4SvJaeC57BL6C57BL6JC57BL6NTacSJLJEsrp1tm11RpcEsrp1tm11RpcEsrp2tm1KOMPVlcgEsrp2tm1KOMPVlcgTgKRT14cre43Smr0Esrp2tm1KOMPVlcgTgKRT14cre43SmrEsrp1tm11Rpc

impaired skin barrier function_Esrp1<tm1.1Rpc>/Esrp1<tm1.1Rpc>,Esrp2<tm1(KOMP)Vlcg>/Esrp2<tm1(KOMP)Vlcg>,Tg(KRT14-cre)43Smr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• epithelial splicing regulatory protein 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1924661
• transgene insertion 43, Sarah E Millar
  http://metadb.riken.jp/db/mgi_rdf/MGI:3046572
• epithelial splicing regulatory protein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1917326

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Esrp1<tm1.1Rpc>/Esrp1<tm1.1Rpc>,Esrp2<tm1(KOMP)Vlcg>/Esrp2<tm1(KOMP)Vlcg>,Tg(KRT14-cre)43Smr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Esrp2<tm1(KOMP)Vlcg>|Tg(KRT14-cre)43Smr|Esrp1<tm1.1Rpc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * C57BL/6J * C57BL/6NTac * SJL/J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired skin barrier function
  http://purl.obolibrary.org/obo/MP_0002796

文献

http://purl.org/net/cito/citesAsAuthority

• Thomas W. Bebee, et.al., The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development., eLife, 2015, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/26371508