impaired skin barrier function_Prss8<tm1.1Bug>/Prss8<Gt(IST10122F12)Tigm>

http://metadb.riken.jp/0002796I129S6SvEvTacBlackSwissC57BL6JC57BL6NPrss8tm11BugPrss8GtIST10122F12TigmPrss8tm11BugPrss8GtIST10122F12Tigm

impaired skin barrier function_Prss8<tm1.1Bug>/Prss8<Gt(IST10122F12)Tigm>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• protease, serine 8 (prostasin)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1923810

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Prss8<tm1.1Bug>/Prss8<Gt(IST10122F12)Tigm>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Prss8<tm1.1Bug>|Prss8<Gt(IST10122F12)Tigm>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * Black Swiss * C57BL/6J * C57BL/6N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired skin barrier function
  http://purl.obolibrary.org/obo/MP_0002796

文献

http://purl.org/net/cito/citesAsAuthority

• Diane E. Peters, et.al., The membrane-anchored serine protease prostasin (CAP1/PRSS8) supports epidermal development and postnatal homeostasis independent of its enzymatic activity., The Journal of biological chemistry, 2014, 289
  http://rdf.ncbi.nlm.nih.gov/pubmed/24706745