decreased heart weight_Akt1<tm1Zzy>/Akt1<tm1Zzy>,Akt3<tm1Hem>/Akt3<tm1Hem>,Tg(Myhc-cre)1Xya/0

http://metadb.riken.jp/0002834I129P2OlaHsdFVBAkt1tm1ZzyAkt1tm1ZzyAkt3tm1HemAkt3tm1HemTgMyhccre1Xya0Akt3tm1HemAkt1tm1ZzyTgMyhccre1Xya

decreased heart weight_Akt1<tm1Zzy>/Akt1<tm1Zzy>,Akt3<tm1Hem>/Akt3<tm1Hem>,Tg(Myhc-cre)1Xya/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• thymoma viral proto-oncogene 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:87986
• thymoma viral proto-oncogene 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1345147
• transgene insertion 1, Xiao Yang
  http://metadb.riken.jp/db/mgi_rdf/MGI:3690219

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Akt1<tm1Zzy>/Akt1<tm1Zzy>,Akt3<tm1Hem>/Akt3<tm1Hem>,Tg(Myhc-cre)1Xya/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Akt3<tm1Hem>|Akt1<tm1Zzy>|Tg(Myhc-cre)1Xya

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased heart weight
  http://purl.obolibrary.org/obo/MP_0002834

文献

http://purl.org/net/cito/citesAsAuthority

• Ruomin. Di, et.al., S6K inhibition renders cardiac protection against myocardial infarction through PDK1 phosphorylation of Akt., The Biochemical journal, 2012, 441
  http://rdf.ncbi.nlm.nih.gov/pubmed/21906027