decreased heart weight_Kdm4a<tm1Zpl>/Kdm4a<tm1Zpl>,Tg(Myh6-cre)1Jmk/0

http://metadb.riken.jp/0002834I129S6SvEvC57BL6Kdm4atm1ZplKdm4atm1ZplTgMyh6cre1Jmk0Kdm4atm1ZplTgMyh6cre1Jmk

decreased heart weight_Kdm4a<tm1Zpl>/Kdm4a<tm1Zpl>,Tg(Myh6-cre)1Jmk/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• lysine (K)-specific demethylase 4A
  http://metadb.riken.jp/db/mgi_rdf/MGI:2446210
• transgene insertion 1, Jeffery D Molkentin
  http://metadb.riken.jp/db/mgi_rdf/MGI:3779098

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kdm4a<tm1Zpl>/Kdm4a<tm1Zpl>,Tg(Myh6-cre)1Jmk/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kdm4a<tm1Zpl>|Tg(Myh6-cre)1Jmk

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEv * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased heart weight
  http://purl.obolibrary.org/obo/MP_0002834

文献

http://purl.org/net/cito/citesAsAuthority

• Qing-Jun. Zhang, et.al., The histone trimethyllysine demethylase JMJD2A promotes cardiac hypertrophy in response to hypertrophic stimuli in mice., The Journal of clinical investigation, 2011, 121
  http://rdf.ncbi.nlm.nih.gov/pubmed/21555854