impaired skeletal muscle contractility_Actg1<tm1.2Erv>/Actg1<tm1.2Erv>,Tg(ACTA1-cre)79Jme/0

http://metadb.riken.jp/0002841I129S1Sv129X1SvJC57BL6SJLActg1tm12ErvActg1tm12ErvTgACTA1cre79Jme0TgACTA1cre79JmeActg1tm12Erv

impaired skeletal muscle contractility_Actg1<tm1.2Erv>/Actg1<tm1.2Erv>,Tg(ACTA1-cre)79Jme/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• actin, gamma, cytoplasmic 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:87906
• transgene insertion 79, Judith Melki
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447634

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Actg1<tm1.2Erv>/Actg1<tm1.2Erv>,Tg(ACTA1-cre)79Jme/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(ACTA1-cre)79Jme|Actg1<tm1.2Erv>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired skeletal muscle contractility
  http://purl.obolibrary.org/obo/MP_0002841

文献

http://purl.org/net/cito/citesAsAuthority

• Kevin J. Sonnemann, et.al., Cytoplasmic gamma-actin is not required for skeletal muscle development but its absence leads to a progressive myopathy., Developmental cell, 2006, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/16950128