abnormal neuron morphology_Gt(ROSA)26Sor<tm1Lrsn>/Gt(ROSA)26Sor<+>,Slc6a3<tm1(cre)Lrsn>/Slc6a3<+>,Tfam<tm1Lrsn>/Tfam<tm1Lrsn>

http://metadb.riken.jp/0002882I129S1Sv129X1SvJC57BL6GtROSA26Sortm1LrsnGtROSA26SorSlc6a3tm1creLrsnSlc6a3Tfamtm1LrsnTfamtm1LrsnSlc6a3tm1creLrsnTfamtm1LrsnSlc6a3GtROSA26SorGtROSA26Sortm1Lrsn

abnormal neuron morphology_Gt(ROSA)26Sor<tm1Lrsn>/Gt(ROSA)26Sor<+>,Slc6a3<tm1(cre)Lrsn>/Slc6a3<+>,Tfam<tm1Lrsn>/Tfam<tm1Lrsn>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:94862
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• transcription factor A, mitochondrial
  http://metadb.riken.jp/db/mgi_rdf/MGI:107810

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1Lrsn>/Gt(ROSA)26Sor<+>,Slc6a3<tm1(cre)Lrsn>/Slc6a3<+>,Tfam<tm1Lrsn>/Tfam<tm1Lrsn>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Slc6a3<tm1(cre)Lrsn>|Tfam<tm1Lrsn>|Slc6a3<+>|Gt(ROSA)26Sor<+>|Gt(ROSA)26Sor<tm1Lrsn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal neuron morphology
  http://purl.obolibrary.org/obo/MP_0002882

文献

http://purl.org/net/cito/citesAsAuthority

• Fredrik H. Sterky, et.al., Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivo., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108
  http://rdf.ncbi.nlm.nih.gov/pubmed/21768369