abnormal neuron morphology_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-LRRK2*)D10Cai/0,Tg(tetO-SNCA*A53T)E2Cai/0

http://metadb.riken.jp/0002882IC57BL6TgCamk2atTA1Mmay0TgtetOLRRK2D10Cai0TgtetOSNCAA53TE2Cai0TgtetOSNCAA53TE2CaiTgCamk2atTA1MmayTgtetOLRRK2D10Cai

abnormal neuron morphology_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-LRRK2*)D10Cai/0,Tg(tetO-SNCA*A53T)E2Cai/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion D10, Huaibin Cai
  http://metadb.riken.jp/db/mgi_rdf/MGI:4420813
• transgene insertion E2, Huaibin Cai
  http://metadb.riken.jp/db/mgi_rdf/MGI:4420800
• transgene insertion 1, Mark Mayford
  http://metadb.riken.jp/db/mgi_rdf/MGI:2179062

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-LRRK2*)D10Cai/0,Tg(tetO-SNCA*A53T)E2Cai/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(tetO-SNCA*A53T)E2Cai|Tg(Camk2a-tTA)1Mmay|Tg(tetO-LRRK2*)D10Cai

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal neuron morphology
  http://purl.obolibrary.org/obo/MP_0002882

文献

http://purl.org/net/cito/citesAsAuthority

• Xian. Lin, et.al., Leucine-rich repeat kinase 2 regulates the progression of neuropathology induced by Parkinson's-disease-related mutant alpha-synuclein., Neuron, 2009, 64
  http://rdf.ncbi.nlm.nih.gov/pubmed/20064389