decreased susceptibility to pharmacologically induced seizures_Scn8a<med-jo>/Scn8a<+>

http://metadb.riken.jp/0002887B6D2Scn8amedjoJScn8amedjoScn8aScn8amedjoScn8a

decreased susceptibility to pharmacologically induced seizures_Scn8a<med-jo>/Scn8a<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• sodium channel, voltage-gated, type VIII, alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:103169

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Scn8a<med-jo>/Scn8a<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Scn8a<med-jo>|Scn8a<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6.D2-Scn8a<med-jo>/J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased susceptibility to pharmacologically induced seizures
  http://purl.obolibrary.org/obo/MP_0002887

文献

http://purl.org/net/cito/citesAsAuthority

• Nicole A. Hawkins, et.al., Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus., Neurobiology of disease, 2011, 41
  http://rdf.ncbi.nlm.nih.gov/pubmed/21156207
• Melinda S. Martin, et.al., The voltage-gated sodium channel Scn8a is a genetic modifier of severe myoclonic epilepsy of infancy., Human molecular genetics, 2007, 16
  http://rdf.ncbi.nlm.nih.gov/pubmed/17881658