abnormal NMDA-mediated synaptic currents_Grin1<tm1c(EUCOMM)Wtsi>/Grin1<tm2.1Stl>,Tg(Slc6a4-cre)ET127Gsat/0

http://metadb.riken.jp/0002888I129S4SvJaeC57BL6FVBNSJLGrin1tm1cEUCOMMWtsiGrin1tm21StlTgSlc6a4creET127Gsat0Grin1tm1cEUCOMMWtsiGrin1tm21StlTgSlc6a4creET127Gsat

abnormal NMDA-mediated synaptic currents_Grin1<tm1c(EUCOMM)Wtsi>/Grin1<tm2.1Stl>,Tg(Slc6a4-cre)ET127Gsat/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• glutamate receptor, ionotropic, NMDA1 (zeta 1)
  http://metadb.riken.jp/db/mgi_rdf/MGI:95819
• transgene insertion ET127, GENSAT Project at Rockefeller University
  http://metadb.riken.jp/db/mgi_rdf/MGI:4367072

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Grin1<tm1c(EUCOMM)Wtsi>/Grin1<tm2.1Stl>,Tg(Slc6a4-cre)ET127Gsat/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Grin1<tm1c(EUCOMM)Wtsi>|Grin1<tm2.1Stl>|Tg(Slc6a4-cre)ET127Gsat

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal NMDA-mediated synaptic currents
  http://purl.obolibrary.org/obo/MP_0002888

文献

http://purl.org/net/cito/citesAsAuthority

• Zhong-wei. Zhang, et.al., Essential role of postsynaptic NMDA receptors in developmental refinement of excitatory synapses., Proceedings of the National Academy of Sciences of the United States of America, 2013, 110
  http://rdf.ncbi.nlm.nih.gov/pubmed/23277569