increased insulin sensitivity_Lepr<db>/Lepr<db>,Repin1<tm1.2Arte>/Repin1<tm1.2Arte>

http://metadb.riken.jp/0002891IBALBcC57BL6C57BLKSJLeprdbLeprdbRepin1tm12ArteRepin1tm12ArteLeprdbRepin1tm12Arte

increased insulin sensitivity_Lepr<db>/Lepr<db>,Repin1<tm1.2Arte>/Repin1<tm1.2Arte>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• leptin receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:104993
• replication initiator 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1889817

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lepr<db>/Lepr<db>,Repin1<tm1.2Arte>/Repin1<tm1.2Arte>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lepr<db>|Repin1<tm1.2Arte>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: BALB/c * C57BL/6 * C57BLKS/J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased insulin sensitivity
  http://purl.obolibrary.org/obo/MP_0002891

文献

http://purl.org/net/cito/citesAsAuthority

• Anne. Kunath, et.al., Repin1 deficiency improves insulin sensitivity and glucose metabolism in db/db mice by reducing adipose tissue mass and inflammation., Biochemical and biophysical research communications, 2016, 478
  http://rdf.ncbi.nlm.nih.gov/pubmed/27402271