increased susceptibility to pharmacologically induced seizures_Gabrg2<tm2Spet>/Gabrg2<+>,Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-cre)LC1Bjd/0

http://metadb.riken.jp/0002906I129S1Sv129X1SvJBALBcC57BL6Gabrg2tm2SpetGabrg2TgCamk2atTA1Mmay0TgtetOcreLC1Bjd0TgtetOcreLC1BjdGabrg2TgCamk2atTA1MmayGabrg2tm2Spet

increased susceptibility to pharmacologically induced seizures_Gabrg2<tm2Spet>/Gabrg2<+>,Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-cre)LC1Bjd/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion LC1, Hermann Bujard
  http://metadb.riken.jp/db/mgi_rdf/MGI:2671943
• gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:95623
• transgene insertion 1, Mark Mayford
  http://metadb.riken.jp/db/mgi_rdf/MGI:2179062

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gabrg2<tm2Spet>/Gabrg2<+>,Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-cre)LC1Bjd/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(tetO-cre)LC1Bjd|Gabrg2<+>|Tg(Camk2a-tTA)1Mmay|Gabrg2<tm2Spet>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to pharmacologically induced seizures
  http://purl.obolibrary.org/obo/MP_0002906

文献

http://purl.org/net/cito/citesAsAuthority

• Cindy. Chiu, et.al., Developmental impact of a familial GABAA receptor epilepsy mutation., Annals of neurology, 2008, 64
  http://rdf.ncbi.nlm.nih.gov/pubmed/18825662