increased susceptibility to pharmacologically induced seizures_Scn2b<tm1Isom>/Scn2b<tm1Isom>

http://metadb.riken.jp/0002906I129S1Sv129X1SvJC57BL6JScn2btm1IsomScn2btm1IsomScn2btm1Isom

increased susceptibility to pharmacologically induced seizures_Scn2b<tm1Isom>/Scn2b<tm1Isom>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• sodium channel, voltage-gated, type II, beta
  http://metadb.riken.jp/db/mgi_rdf/MGI:106921

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Scn2b<tm1Isom>/Scn2b<tm1Isom>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Scn2b<tm1Isom>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to pharmacologically induced seizures
  http://purl.obolibrary.org/obo/MP_0002906

文献

http://purl.org/net/cito/citesAsAuthority

• Chunling. Chen, et.al., Reduced sodium channel density, altered voltage dependence of inactivation, and increased susceptibility to seizures in mice lacking sodium channel beta 2-subunits., Proceedings of the National Academy of Sciences of the United States of America, 2002, 99
  http://rdf.ncbi.nlm.nih.gov/pubmed/12481039