abnormal excitatory postsynaptic potential_Prnp<tm1Cwe>/Prnp<tm1Cwe>,Tg(Nefh-cre)22Jcol/?,Tg(Prnp)37Jcol/?

http://metadb.riken.jp/0002912I129Sv129S7SvEvBrdC57BL6FVBPrnptm1CwePrnptm1CweTgNefhcre22JcolTgPrnp37JcolTgPrnp37JcolPrnptm1CweTgNefhcre22Jcol

abnormal excitatory postsynaptic potential_Prnp<tm1Cwe>/Prnp<tm1Cwe>,Tg(Nefh-cre)22Jcol/?,Tg(Prnp)37Jcol/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 22, John Collinge
  http://metadb.riken.jp/db/mgi_rdf/MGI:3761835
• transgene insertion 37, John Collinge
  http://metadb.riken.jp/db/mgi_rdf/MGI:3761837
• prion protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:97769

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Prnp<tm1Cwe>/Prnp<tm1Cwe>,Tg(Nefh-cre)22Jcol/?,Tg(Prnp)37Jcol/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Prnp)37Jcol|Prnp<tm1Cwe>|Tg(Nefh-cre)22Jcol

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * 129S7/SvEvBrd * C57BL/6 * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal excitatory postsynaptic potential
  http://purl.obolibrary.org/obo/MP_0002912

文献

http://purl.org/net/cito/citesAsAuthority

• Giovanna R. Mallucci, et.al., Targeting cellular prion protein reverses early cognitive deficits and neurophysiological dysfunction in prion-infected mice., Neuron, 2007, 53
  http://rdf.ncbi.nlm.nih.gov/pubmed/17270731