increased circulating alanine transaminase level_Abcb4<tm1Bor>/Abcb4<tm1Bor>,Tg(ABCG5/ABCG8)14-2Hobb/0

http://metadb.riken.jp/0002941I129P2OlaHsdC57BL6JFVBNSJLAbcb4tm1BorAbcb4tm1BorTgABCG5ABCG8142Hobb0TgABCG5ABCG8142HobbAbcb4tm1Bor

increased circulating alanine transaminase level_Abcb4<tm1Bor>/Abcb4<tm1Bor>,Tg(ABCG5/ABCG8)14-2Hobb/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• ATP-binding cassette, sub-family B (MDR/TAP), member 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:97569
• transgene insertion 14-2, Helen H Hobbs
  http://metadb.riken.jp/db/mgi_rdf/MGI:2446955

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Abcb4<tm1Bor>/Abcb4<tm1Bor>,Tg(ABCG5/ABCG8)14-2Hobb/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(ABCG5/ABCG8)14-2Hobb|Abcb4<tm1Bor>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6J * FVB/N * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating alanine transaminase level
  http://purl.obolibrary.org/obo/MP_0002941

文献

http://purl.org/net/cito/citesAsAuthority

• Silvia. Langheim, et.al., ABCG5 and ABCG8 require MDR2 for secretion of cholesterol into bile., Journal of lipid research, 2005, 46
  http://rdf.ncbi.nlm.nih.gov/pubmed/15930516