increased circulating alanine transaminase level_Nfe2l1<tm1Jefc>/Nfe2l1<tm1Ywk>,Tg(Alb-cre)21Mgn/0

http://metadb.riken.jp/0002941I129X1SvJC57BL6JNfe2l1tm1JefcNfe2l1tm1YwkTgAlbcre21Mgn0TgAlbcre21MgnNfe2l1tm1YwkNfe2l1tm1Jefc

increased circulating alanine transaminase level_Nfe2l1<tm1Jefc>/Nfe2l1<tm1Ywk>,Tg(Alb-cre)21Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226
• nuclear factor, erythroid derived 2,-like 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:99421

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nfe2l1<tm1Jefc>/Nfe2l1<tm1Ywk>,Tg(Alb-cre)21Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Alb-cre)21Mgn|Nfe2l1<tm1Ywk>|Nfe2l1<tm1Jefc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating alanine transaminase level
  http://purl.obolibrary.org/obo/MP_0002941

文献

http://purl.org/net/cito/citesAsAuthority

• Zhenrong. Xu, et.al., Liver-specific inactivation of the Nrf1 gene in adult mouse leads to nonalcoholic steatohepatitis and hepatic neoplasia., Proceedings of the National Academy of Sciences of the United States of America, 2005, 102
  http://rdf.ncbi.nlm.nih.gov/pubmed/15738389