increased intestinal adenocarcinoma incidence_Apc<tm1Rak>/Apc<+>,Cdh1<tm1Cbm>/Cdh1<+>

http://metadb.riken.jp/0002957I129P2OlaHsdC57BL6JApctm1RakApcCdh1tm1CbmCdh1Apctm1RakApcCdh1Cdh1tm1Cbm

increased intestinal adenocarcinoma incidence_Apc<tm1Rak>/Apc<+>,Cdh1<tm1Cbm>/Cdh1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• adenomatosis polyposis coli
  http://metadb.riken.jp/db/mgi_rdf/MGI:88039
• cadherin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88354

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apc<tm1Rak>/Apc<+>,Cdh1<tm1Cbm>/Cdh1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Apc<tm1Rak>|Apc<+>|Cdh1<+>|Cdh1<tm1Cbm>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased intestinal adenocarcinoma incidence
  http://purl.obolibrary.org/obo/MP_0002957

文献

http://purl.org/net/cito/citesAsAuthority

• R. Smits, et.al., E-cadherin and adenomatous polyposis coli mutations are synergistic in intestinal tumor initiation in mice., Gastroenterology, 2000, 119
  http://rdf.ncbi.nlm.nih.gov/pubmed/11040191