increased intestinal adenocarcinoma incidence_Apc<Min>/Apc<+>,Tgfbr1<tm1Bopa>/Tgfbr1<+>

http://metadb.riken.jp/0002957I129S1SvImJC57BL6JApcMinApcTgfbr1tm1BopaTgfbr1Tgfbr1tm1BopaApcApcMinTgfbr1

increased intestinal adenocarcinoma incidence_Apc<Min>/Apc<+>,Tgfbr1<tm1Bopa>/Tgfbr1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transforming growth factor, beta receptor I
  http://metadb.riken.jp/db/mgi_rdf/MGI:98728
• adenomatosis polyposis coli
  http://metadb.riken.jp/db/mgi_rdf/MGI:88039

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apc<Min>/Apc<+>,Tgfbr1<tm1Bopa>/Tgfbr1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tgfbr1<tm1Bopa>|Apc<+>|Apc<Min>|Tgfbr1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/SvImJ * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased intestinal adenocarcinoma incidence
  http://purl.obolibrary.org/obo/MP_0002957

文献

http://purl.org/net/cito/citesAsAuthority

• Qinghua. Zeng, et.al., Tgfbr1 haploinsufficiency is a potent modifier of colorectal cancer development., Cancer research, 2009, 69
  http://rdf.ncbi.nlm.nih.gov/pubmed/19147584