increased intestinal adenocarcinoma incidence_Dnmt1<tm1Pwl>/Dnmt1<+>,Mlh1<tm1Lisk>/Mlh1<tm1Lisk>

http://metadb.riken.jp/0002957I129S4SvJae129S7SvEvBrdC57BL6Dnmt1tm1PwlDnmt1Mlh1tm1LiskMlh1tm1LiskMlh1tm1LiskDnmt1tm1PwlDnmt1

increased intestinal adenocarcinoma incidence_Dnmt1<tm1Pwl>/Dnmt1<+>,Mlh1<tm1Lisk>/Mlh1<tm1Lisk>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• mutL homolog 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:101938
• DNA methyltransferase (cytosine-5) 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:94912

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Dnmt1<tm1Pwl>/Dnmt1<+>,Mlh1<tm1Lisk>/Mlh1<tm1Lisk>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mlh1<tm1Lisk>|Dnmt1<tm1Pwl>|Dnmt1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased intestinal adenocarcinoma incidence
  http://purl.obolibrary.org/obo/MP_0002957

文献

http://purl.org/net/cito/citesAsAuthority

• Binh N. Trinh, et.al., DNA methyltransferase deficiency modifies cancer susceptibility in mice lacking DNA mismatch repair., Molecular and cellular biology, 2002, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/11940649