increased circulating alkaline phosphatase level_Lmna<tm1.1Otin>/Lmna<+>

http://metadb.riken.jp/0002968I129P2OlaHsdC57BL6Lmnatm11OtinLmnaLmnatm11OtinLmna

increased circulating alkaline phosphatase level_Lmna<tm1.1Otin>/Lmna<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• lamin A
  http://metadb.riken.jp/db/mgi_rdf/MGI:96794

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lmna<tm1.1Otin>/Lmna<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lmna<tm1.1Otin>|Lmna<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating alkaline phosphatase level
  http://purl.obolibrary.org/obo/MP_0002968

文献

http://purl.org/net/cito/citesAsAuthority

• Ricardo. Villa-Bellosta, et.al., Defective extracellular pyrophosphate metabolism promotes vascular calcification in a mouse model of Hutchinson-Gilford progeria syndrome that is ameliorated on pyrophosphate treatment., Circulation, 2013, 127
  http://rdf.ncbi.nlm.nih.gov/pubmed/23690466