decreased urine osmolality_Adcy6<tm1.1Dek>/Adcy6<tm1.1Dek>,Tg(Aqp2-cre)1Dek/0

http://metadb.riken.jp/0002988I129X1SvJC57BL6SJLAdcy6tm11DekAdcy6tm11DekTgAqp2cre1Dek0Adcy6tm11DekTgAqp2cre1Dek

decreased urine osmolality_Adcy6<tm1.1Dek>/Adcy6<tm1.1Dek>,Tg(Aqp2-cre)1Dek/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• adenylate cyclase 6
  http://metadb.riken.jp/db/mgi_rdf/MGI:87917
• transgene insertion 1, Donald E Kohan
  http://metadb.riken.jp/db/mgi_rdf/MGI:3712434

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Adcy6<tm1.1Dek>/Adcy6<tm1.1Dek>,Tg(Aqp2-cre)1Dek/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Adcy6<tm1.1Dek>|Tg(Aqp2-cre)1Dek

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased urine osmolality
  http://purl.obolibrary.org/obo/MP_0002988

文献

http://purl.org/net/cito/citesAsAuthority

• Karl P. Roos, et.al., Collecting duct-specific knockout of adenylyl cyclase type VI causes a urinary concentration defect in mice., American journal of physiology. Renal physiology, 2012, 302
  http://rdf.ncbi.nlm.nih.gov/pubmed/21937603