primary sex reversal_Mapk11<tm1Jsca>/Mapk11<+>,Mapk14<tm2Nbr>/Mapk14<tm2Nbr>,Tg(Sox2-cre)1Amc/0

http://metadb.riken.jp/0002995I129P2OlaHsdC57BL6CBAMapk11tm1JscaMapk11Mapk14tm2NbrMapk14tm2NbrTgSox2cre1Amc0Mapk11tm1JscaTgSox2cre1AmcMapk11Mapk14tm2Nbr

primary sex reversal_Mapk11<tm1Jsca>/Mapk11<+>,Mapk14<tm2Nbr>/Mapk14<tm2Nbr>,Tg(Sox2-cre)1Amc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• mitogen-activated protein kinase 14
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346865
• mitogen-activated protein kinase 11
  http://metadb.riken.jp/db/mgi_rdf/MGI:1338024
• transgene insertion 1, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2656537

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mapk11<tm1Jsca>/Mapk11<+>,Mapk14<tm2Nbr>/Mapk14<tm2Nbr>,Tg(Sox2-cre)1Amc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mapk11<tm1Jsca>|Tg(Sox2-cre)1Amc|Mapk11<+>|Mapk14<tm2Nbr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• primary sex reversal
  http://purl.obolibrary.org/obo/MP_0002995

文献

http://purl.org/net/cito/citesAsAuthority

• Nick. Warr, et.al., Gadd45γ and Map3k4 interactions regulate mouse testis determination via p38 MAPK-mediated control of Sry expression., Developmental cell, 2012, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/23102580