abnormal cytokine secretion_Zap70<tm1.1Mmal>/Zap70<tm1.1Mmal>,Tg(TcrLCMV)327Sdz/0

http://metadb.riken.jp/0003009I129P2OlaHsdBALBcJC57BL6DBA2Zap70tm11MmalZap70tm11MmalTgTcrLCMV327Sdz0Zap70tm11MmalTgTcrLCMV327Sdz

abnormal cytokine secretion_Zap70<tm1.1Mmal>/Zap70<tm1.1Mmal>,Tg(TcrLCMV)327Sdz/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 327, Birgit Ledermann
  http://metadb.riken.jp/db/mgi_rdf/MGI:2665109
• zeta-chain (TCR) associated protein kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:99613

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Zap70<tm1.1Mmal>/Zap70<tm1.1Mmal>,Tg(TcrLCMV)327Sdz/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Zap70<tm1.1Mmal>|Tg(TcrLCMV)327Sdz

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * BALB/cJ * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal cytokine secretion
  http://purl.obolibrary.org/obo/MP_0003009

文献

http://purl.org/net/cito/citesAsAuthority

• A. Magnan, et.al., T cell development and T cell responses in mice with mutations affecting tyrosines 292 or 315 of the ZAP-70 protein tyrosine kinase., The Journal of experimental medicine, 2001, 194
  http://rdf.ncbi.nlm.nih.gov/pubmed/11514605