increased vasoconstriction_Appl1<tm1Ymli>/Appl1<tm1Ymli>

http://metadb.riken.jp/0003025I129S1SvC57BL6JAppl1tm1YmliAppl1tm1YmliAppl1tm1Ymli

increased vasoconstriction_Appl1<tm1Ymli>/Appl1<tm1Ymli>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1920243

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Appl1<tm1Ymli>/Appl1<tm1Ymli>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Appl1<tm1Ymli>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased vasoconstriction
  http://purl.obolibrary.org/obo/MP_0003025

文献

http://purl.org/net/cito/citesAsAuthority

• Yi. Wang, et.al., APPL1 counteracts obesity-induced vascular insulin resistance and endothelial dysfunction by modulating the endothelial production of nitric oxide and endothelin-1 in mice., Diabetes, 2011, 60
  http://rdf.ncbi.nlm.nih.gov/pubmed/21926268