decreased vasoconstriction_Tg(Notch3*R169C)88Bbb/0

http://metadb.riken.jp/0003026IFVBNTgNotch3R169C88Bbb0TgNotch3R169C88Bbb

decreased vasoconstriction_Tg(Notch3*R169C)88Bbb/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 88, Norbert Hubner
  http://metadb.riken.jp/db/mgi_rdf/MGI:4429554

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Notch3*R169C)88Bbb/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Notch3*R169C)88Bbb

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased vasoconstriction
  http://purl.obolibrary.org/obo/MP_0003026

文献

http://purl.org/net/cito/citesAsAuthority

• Fabrice. Dabertrand, et.al., Potassium channelopathy-like defect underlies early-stage cerebrovascular dysfunction in a genetic model of small vessel disease., Proceedings of the National Academy of Sciences of the United States of America, 2015, 112
  http://rdf.ncbi.nlm.nih.gov/pubmed/25646445
• Anne. Joutel, et.al., Cerebrovascular dysfunction and microcirculation rarefaction precede white matter lesions in a mouse genetic model of cerebral ischemic small vessel disease., The Journal of clinical investigation, 2010, 120
  http://rdf.ncbi.nlm.nih.gov/pubmed/20071773