spina bifida_Sfrp1<tm1Aksh>/Sfrp1<tm1Aksh>,Sfrp2<tm1Aksh>/Sfrp2<+>,Sfrp5<tm1Aksh>/Sfrp5<tm1Aksh>,Vangl2<Lp>/Vangl2<+>

http://metadb.riken.jp/0003054I129AC57BL6LPTLeJSfrp1tm1AkshSfrp1tm1AkshSfrp2tm1AkshSfrp2Sfrp5tm1AkshSfrp5tm1AkshVangl2LpVangl2Vangl2Sfrp2tm1AkshSfrp2Sfrp1tm1AkshSfrp5tm1AkshVangl2Lp

spina bifida_Sfrp1<tm1Aksh>/Sfrp1<tm1Aksh>,Sfrp2<tm1Aksh>/Sfrp2<+>,Sfrp5<tm1Aksh>/Sfrp5<tm1Aksh>,Vangl2<Lp>/Vangl2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• secreted frizzled-related protein 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:108078
• secreted frizzled-related sequence protein 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:1860298
• vang-like 2 (van gogh, Drosophila)
  http://metadb.riken.jp/db/mgi_rdf/MGI:2135272
• secreted frizzled-related protein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:892014

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sfrp1<tm1Aksh>/Sfrp1<tm1Aksh>,Sfrp2<tm1Aksh>/Sfrp2<+>,Sfrp5<tm1Aksh>/Sfrp5<tm1Aksh>,Vangl2<Lp>/Vangl2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Vangl2<+>|Sfrp2<tm1Aksh>|Sfrp2<+>|Sfrp1<tm1Aksh>|Sfrp5<tm1Aksh>|Vangl2<Lp>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * A * C57BL/6 * LPT/LeJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• spina bifida
  http://purl.obolibrary.org/obo/MP_0003054

文献

http://purl.org/net/cito/citesAsAuthority

• Wataru. Satoh, et.al., Sfrp1, Sfrp2, and Sfrp5 regulate the Wnt/beta-catenin and the planar cell polarity pathways during early trunk formation in mouse., Genesis (New York, N.Y. : 2000), 2008, 46
  http://rdf.ncbi.nlm.nih.gov/pubmed/18257070