spina bifida_Gnaz<tm1Lfb>/Gnaz<tm1Lfb>,Grhl3<tm1(cre)Cgh>/Grhl3<+>,Gt(ROSA)26Sor<tm1(ptxA)Cgh>/Gt(ROSA)26Sor<+>

http://metadb.riken.jp/0003054I129P2OlaHsdC57BL6SJLGnaztm1LfbGnaztm1LfbGrhl3tm1creCghGrhl3GtROSA26Sortm1ptxACghGtROSA26SorGtROSA26Sortm1ptxACghGtROSA26SorGnaztm1LfbGrhl3Grhl3tm1creCgh

spina bifida_Gnaz<tm1Lfb>/Gnaz<tm1Lfb>,Grhl3<tm1(cre)Cgh>/Grhl3<+>,Gt(ROSA)26Sor<tm1(ptxA)Cgh>/Gt(ROSA)26Sor<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• grainyhead-like 3 (Drosophila)
  http://metadb.riken.jp/db/mgi_rdf/MGI:2655333
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• guanine nucleotide binding protein, alpha z subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:95780

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gnaz<tm1Lfb>/Gnaz<tm1Lfb>,Grhl3<tm1(cre)Cgh>/Grhl3<+>,Gt(ROSA)26Sor<tm1(ptxA)Cgh>/Gt(ROSA)26Sor<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm1(ptxA)Cgh>|Gt(ROSA)26Sor<+>|Gnaz<tm1Lfb>|Grhl3<+>|Grhl3<tm1(cre)Cgh>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• spina bifida
  http://purl.obolibrary.org/obo/MP_0003054

文献

http://purl.org/net/cito/citesAsAuthority

• Eric. Camerer, et.al., Local protease signaling contributes to neural tube closure in the mouse embryo., Developmental cell, 2010, 18
  http://rdf.ncbi.nlm.nih.gov/pubmed/20152175