decreased insulin secretion_Glud1<tm1.1Pma>/Glud1<tm1.1Pma>,Tg(Ins2-cre)23Herr/0

http://metadb.riken.jp/0003059I129S1Sv129X1SvJC57BL6CBAJSJLGlud1tm11PmaGlud1tm11PmaTgIns2cre23Herr0TgIns2cre23HerrGlud1tm11Pma

decreased insulin secretion_Glud1<tm1.1Pma>/Glud1<tm1.1Pma>,Tg(Ins2-cre)23Herr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• glutamate dehydrogenase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:95753
• transgene insertion 23, Pedro Luis Herrera
  http://metadb.riken.jp/db/mgi_rdf/MGI:4431238

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Glud1<tm1.1Pma>/Glud1<tm1.1Pma>,Tg(Ins2-cre)23Herr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Ins2-cre)23Herr|Glud1<tm1.1Pma>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA/J * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased insulin secretion
  http://purl.obolibrary.org/obo/MP_0003059

文献

http://purl.org/net/cito/citesAsAuthority

• Stefania. Carobbio, et.al., Deletion of glutamate dehydrogenase in beta-cells abolishes part of the insulin secretory response not required for glucose homeostasis., The Journal of biological chemistry, 2009, 284
  http://rdf.ncbi.nlm.nih.gov/pubmed/19015267