decreased insulin secretion_Selenot<tm1.1Ics>/Selenot<tm1.1Ics>,Tg(Ins2-cre)25Mgn/0

http://metadb.riken.jp/0003059I129S2SvPasC57BL6C57BL6JDBASelenottm11IcsSelenottm11IcsTgIns2cre25Mgn0Selenottm11IcsTgIns2cre25Mgn

decreased insulin secretion_Selenot<tm1.1Ics>/Selenot<tm1.1Ics>,Tg(Ins2-cre)25Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 25, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176225
• selenoprotein T
  http://metadb.riken.jp/db/mgi_rdf/MGI:1916477

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Selenot<tm1.1Ics>/Selenot<tm1.1Ics>,Tg(Ins2-cre)25Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Selenot<tm1.1Ics>|Tg(Ins2-cre)25Mgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6 * C57BL/6J * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased insulin secretion
  http://purl.obolibrary.org/obo/MP_0003059

文献

http://purl.org/net/cito/citesAsAuthority

• Gaëtan. Prevost, et.al., The PACAP-regulated gene selenoprotein T is abundantly expressed in mouse and human β-cells and its targeted inactivation impairs glucose tolerance., Endocrinology, 2013, 154
  http://rdf.ncbi.nlm.nih.gov/pubmed/23913443