decreased insulin secretion_Ero1lb<Gt(P077G11)Wrst>/Ero1lb<+>,Ins2<Akita>/Ins2<+>

http://metadb.riken.jp/0003059I129S2SvPasC57BL6NSlcEro1lbGtP077G11WrstEro1lbIns2AkitaIns2Ero1lbGtP077G11WrstIns2Ero1lbIns2Akita

decreased insulin secretion_Ero1lb<Gt(P077G11)Wrst>/Ero1lb<+>,Ins2<Akita>/Ins2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• ERO1-like beta (S. cerevisiae)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1914725
• insulin II
  http://metadb.riken.jp/db/mgi_rdf/MGI:96573

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ero1lb<Gt(P077G11)Wrst>/Ero1lb<+>,Ins2<Akita>/Ins2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ero1lb<Gt(P077G11)Wrst>|Ins2<+>|Ero1lb<+>|Ins2<Akita>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6NSlc

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased insulin secretion
  http://purl.obolibrary.org/obo/MP_0003059

文献

http://purl.org/net/cito/citesAsAuthority

• Ester. Zito, et.al., ERO1-beta, a pancreas-specific disulfide oxidase, promotes insulin biogenesis and glucose homeostasis., The Journal of cell biology, 2010, 188
  http://rdf.ncbi.nlm.nih.gov/pubmed/20308425