abnormal cell cycle_Mdm4<Gt(VICTR20)7Lex>/Mdm4<Gt(VICTR20)7Lex>,Trp53<tm1Wahl>/Trp53<tm1Wahl>

http://metadb.riken.jp/0003077I129S5SvEvBrdC57BL6Mdm4GtVICTR207LexMdm4GtVICTR207LexTrp53tm1WahlTrp53tm1WahlMdm4GtVICTR207LexTrp53tm1Wahl

abnormal cell cycle_Mdm4<Gt(VICTR20)7Lex>/Mdm4<Gt(VICTR20)7Lex>,Trp53<tm1Wahl>/Trp53<tm1Wahl>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• transformed mouse 3T3 cell double minute 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:107934

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mdm4<Gt(VICTR20)7Lex>/Mdm4<Gt(VICTR20)7Lex>,Trp53<tm1Wahl>/Trp53<tm1Wahl>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mdm4<Gt(VICTR20)7Lex>|Trp53<tm1Wahl>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S5/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal cell cycle
  http://purl.obolibrary.org/obo/MP_0003077

文献

http://purl.org/net/cito/citesAsAuthority

• Franck. Toledo, et.al., A mouse p53 mutant lacking the proline-rich domain rescues Mdm4 deficiency and provides insight into the Mdm2-Mdm4-p53 regulatory network., Cancer cell, 2006, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/16616333