increased early pro-B cell number_Ikzf1<tm1(Pax5)Mbu>/Ikzf1<tm1(Pax5)Mbu>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0003133I129P2OlaHsdC57BL6CBAIkzf1tm1Pax5MbuIkzf1tm1Pax5MbuTgMx1cre1Cgn0Ikzf1tm1Pax5MbuTgMx1cre1Cgn

increased early pro-B cell number_Ikzf1<tm1(Pax5)Mbu>/Ikzf1<tm1(Pax5)Mbu>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• IKAROS family zinc finger 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1342540
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ikzf1<tm1(Pax5)Mbu>/Ikzf1<tm1(Pax5)Mbu>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ikzf1<tm1(Pax5)Mbu>|Tg(Mx1-cre)1Cgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased early pro-B cell number
  http://purl.obolibrary.org/obo/MP_0003133

文献

http://purl.org/net/cito/citesAsAuthority

• Abdallah. Souabni, et.al., Pax5 promotes B lymphopoiesis and blocks T cell development by repressing Notch1., Immunity, 2002, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/12479824