cardiac fibrosis_Fbn1<Tsk>/Fbn1<+>

http://metadb.riken.jp/0003141B6CgFbn1TskFbn1TskFbn1Fbn1TskFbn1

cardiac fibrosis_Fbn1<Tsk>/Fbn1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• fibrillin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:95489

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fbn1<Tsk>/Fbn1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Fbn1<Tsk>|Fbn1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6.Cg-Fbn1<Tsk>

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• cardiac fibrosis
  http://purl.obolibrary.org/obo/MP_0003141

文献

http://purl.org/net/cito/citesAsAuthority

• N. Philips, et.al., Increased alpha 1(I) procollagen gene expression in tight skin (TSK) mice myocardial fibroblasts is due to a reduced interaction of a negative regulatory sequence with AP-1 transcription factor., The Journal of biological chemistry, 1995, 270
  http://rdf.ncbi.nlm.nih.gov/pubmed/7721853
• J. Yao, et.al., Decreased collagen mRNA and regression of cardiac fibrosis in the ventricular myocardium of the tight skin mouse following thyroid hormone treatment., Cardiovascular research, 1992, 26
  http://rdf.ncbi.nlm.nih.gov/pubmed/1451140