cardiac fibrosis_Myh6<tm1Jse>/Myh6<+>,Postn<tm1Jmol>/Postn<tm1Jmol>

http://metadb.riken.jp/0003141I129SSvEv129X1SvJMyh6tm1JseMyh6Postntm1JmolPostntm1JmolMyh6tm1JsePostntm1JmolMyh6

cardiac fibrosis_Myh6<tm1Jse>/Myh6<+>,Postn<tm1Jmol>/Postn<tm1Jmol>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• myosin, heavy polypeptide 6, cardiac muscle, alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:97255
• periostin, osteoblast specific factor
  http://metadb.riken.jp/db/mgi_rdf/MGI:1926321

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Myh6<tm1Jse>/Myh6<+>,Postn<tm1Jmol>/Postn<tm1Jmol>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Myh6<tm1Jse>|Postn<tm1Jmol>|Myh6<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• cardiac fibrosis
  http://purl.obolibrary.org/obo/MP_0003141

文献

http://purl.org/net/cito/citesAsAuthority

• Polakit. Teekakirikul, et.al., Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires Tgf-β., The Journal of clinical investigation, 2010, 120
  http://rdf.ncbi.nlm.nih.gov/pubmed/20811150