cardiac fibrosis_Atp2a2<tm1Ges>/Atp2a2<+>

http://metadb.riken.jp/0003141I129X1SvJBlackSwissAtp2a2tm1GesAtp2a2Atp2a2tm1GesAtp2a2

cardiac fibrosis_Atp2a2<tm1Ges>/Atp2a2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:88110

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Atp2a2<tm1Ges>/Atp2a2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Atp2a2<tm1Ges>|Atp2a2<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * Black Swiss

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• cardiac fibrosis
  http://purl.obolibrary.org/obo/MP_0003141

文献

http://purl.org/net/cito/citesAsAuthority

• Jo El J. Schultz, et.al., Accelerated onset of heart failure in mice during pressure overload with chronically decreased SERCA2 calcium pump activity., American journal of physiology. Heart and circulatory physiology, 2004, 286
  http://rdf.ncbi.nlm.nih.gov/pubmed/14630633
• L H. Liu, et.al., Squamous cell tumors in mice heterozygous for a null allele of Atp2a2, encoding the sarco(endo)plasmic reticulum Ca2+-ATPase isoform 2 Ca2+ pump., The Journal of biological chemistry, 2001, 276
  http://rdf.ncbi.nlm.nih.gov/pubmed/11389134