RDF of MGI data
表現型アノテーション
abnormal telomere length_Terc<tm1Rdp>/Terc<tm1Rdp>
http://metadb.riken.jp/0003155I129SvC57BL6JSJLTerctm1RdpTerctm1RdpTerctm1Rdp
abnormal telomere length_Terc<tm1Rdp>/Terc<tm1Rdp>(表現型アノテーション)
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abnormal telomere length_Terc<tm1Rdp>/Terc<tm1Rdp>
表現型アノテーション
MGI marker
http://metadb.riken.jp/db/mgi_rdf/variant_of
telomerase RNA component
http://metadb.riken.jp/db/mgi_rdf/MGI:109558
遺伝子型
http://metadb.riken.jp/db/mgi_rdf/allele_composition
Terc<tm1Rdp>/Terc<tm1Rdp>
アレルシンボル
http://metadb.riken.jp/db/mgi_rdf/allele_symbol
Terc<tm1Rdp>
遺伝的背景
http://metadb.riken.jp/db/mgi_rdf/genetic_background
involves: 129/Sv * C57BL/6J * SJL
MP annotation
http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype
abnormal telomere length
http://purl.obolibrary.org/obo/MP_0003155
文献
http://purl.org/net/cito/citesAsAuthority
Sonia. Franco, et.al., Decreased B16F10 melanoma growth and impaired vascularization in telomerase-deficient mice with critically short telomeres., Cancer research, 2002, 62
http://rdf.ncbi.nlm.nih.gov/pubmed/11809709
Annarosa. Leri, et.al., Ablation of telomerase and telomere loss leads to cardiac dilatation and heart failure associated with p53 upregulation., The EMBO journal, 2003, 22
http://rdf.ncbi.nlm.nih.gov/pubmed/12505991
Christine M. Khoo, et.al., Ink4a/Arf tumor suppressor does not modulate the degenerative conditions or tumor spectrum of the telomerase-deficient mouse., Proceedings of the National Academy of Sciences of the United States of America, 2007, 104
http://rdf.ncbi.nlm.nih.gov/pubmed/17360455
M A. Blasco, et.al., Telomere shortening and tumor formation by mouse cells lacking telomerase RNA., Cell, 1997, 91
http://rdf.ncbi.nlm.nih.gov/pubmed/9335332
Lin. Liu, et.al., Irregular telomeres impair meiotic synapsis and recombination in mice., Proceedings of the National Academy of Sciences of the United States of America, 2004, 101
http://rdf.ncbi.nlm.nih.gov/pubmed/15084742
E. Herrera, et.al., Telomere shortening in mTR-/- embryos is associated with failure to close the neural tube., The EMBO journal, 1999, 18
http://rdf.ncbi.nlm.nih.gov/pubmed/10064584
E. Herrera, et.al., Impaired germinal center reaction in mice with short telomeres., The EMBO journal, 2000, 19
http://rdf.ncbi.nlm.nih.gov/pubmed/10654945
María Luisa. Cayuela, et.al., The telomerase RNA component Terc is required for the tumour-promoting effects of Tert overexpression., EMBO reports, 2005, 6
http://rdf.ncbi.nlm.nih.gov/pubmed/15731767
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