thrombocytopenia_Dicer1<tm1Mmk>/Dicer1<tm1Mmk>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0

http://metadb.riken.jp/0003179I129C57BL6CD1Dicer1tm1MmkDicer1tm1MmkTgSp7tTAtetOEGFPcre1Amc0Dicer1tm1MmkTgSp7tTAtetOEGFPcre1Amc

thrombocytopenia_Dicer1<tm1Mmk>/Dicer1<tm1Mmk>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:3689349
• dicer 1, ribonuclease type III
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177178

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Dicer1<tm1Mmk>/Dicer1<tm1Mmk>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Dicer1<tm1Mmk>|Tg(Sp7-tTA,tetO-EGFP/cre)1Amc

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * CD-1

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased platelet cell number
  http://purl.obolibrary.org/obo/MP_0003179

文献

http://purl.org/net/cito/citesAsAuthority

• Marc H G P. Raaijmakers, et.al., Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia., Nature, 2010, 464
  http://rdf.ncbi.nlm.nih.gov/pubmed/20305640