thrombocytopenia_Cdc42<tm1Brak>/Cdc42<tm1Brak>,Tg(Pf4-icre)Q3Rsko/0

http://metadb.riken.jp/0003179I129C57BL6Cdc42tm1BrakCdc42tm1BrakTgPf4icreQ3Rsko0Cdc42tm1BrakTgPf4icreQ3Rsko

thrombocytopenia_Cdc42<tm1Brak>/Cdc42<tm1Brak>,Tg(Pf4-icre)Q3Rsko/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cell division cycle 42
  http://metadb.riken.jp/db/mgi_rdf/MGI:106211
• transgene insertion Q3, Radek C Skoda
  http://metadb.riken.jp/db/mgi_rdf/MGI:3764699

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdc42<tm1Brak>/Cdc42<tm1Brak>,Tg(Pf4-icre)Q3Rsko/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cdc42<tm1Brak>|Tg(Pf4-icre)Q3Rsko

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased platelet cell number
  http://purl.obolibrary.org/obo/MP_0003179

文献

http://purl.org/net/cito/citesAsAuthority

• Irina. Pleines, et.al., Multiple alterations of platelet functions dominated by increased secretion in mice lacking Cdc42 in platelets., Blood, 2010, 115
  http://rdf.ncbi.nlm.nih.gov/pubmed/20139097