thrombocytopenia_Cd74<tm1Anjm>/Cd74<+>,Lmo2<tm2(cre)Thr>/Lmo2<+>,Smim3<tm1Anjm>/Smim3<+>

http://metadb.riken.jp/0003179I129P2OlaHsd129S7SvEvBrdC57BL6Cd74tm1AnjmCd74Lmo2tm2creThrLmo2Smim3tm1AnjmSmim3Lmo2tm2creThrCd74Lmo2Smim3Cd74tm1AnjmSmim3tm1Anjm

thrombocytopenia_Cd74<tm1Anjm>/Cd74<+>,Lmo2<tm2(cre)Thr>/Lmo2<+>,Smim3<tm1Anjm>/Smim3<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
  http://metadb.riken.jp/db/mgi_rdf/MGI:96534
• small integral membrane protein 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1917088
• LIM domain only 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:102811

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd74<tm1Anjm>/Cd74<+>,Lmo2<tm2(cre)Thr>/Lmo2<+>,Smim3<tm1Anjm>/Smim3<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lmo2<tm2(cre)Thr>|Cd74<+>|Lmo2<+>|Smim3<+>|Cd74<tm1Anjm>|Smim3<tm1Anjm>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased platelet cell number
  http://purl.obolibrary.org/obo/MP_0003179

文献

http://purl.org/net/cito/citesAsAuthority

• Jillian L. Barlow, et.al., A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- syndrome., Nature medicine, 2010, 16
  http://rdf.ncbi.nlm.nih.gov/pubmed/19966810