thrombocytopenia_Il1r1<tm1Roml>/Il1r1<tm1Roml>,Nlrp1a<Neut1>/Nlrp1a<Neut1>

http://metadb.riken.jp/0003179I129S1SvC57BL6Il1r1tm1RomlIl1r1tm1RomlNlrp1aNeut1Nlrp1aNeut1Nlrp1aNeut1Il1r1tm1Roml

thrombocytopenia_Il1r1<tm1Roml>/Il1r1<tm1Roml>,Nlrp1a<Neut1>/Nlrp1a<Neut1>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• NLR family, pyrin domain containing 1A
  http://metadb.riken.jp/db/mgi_rdf/MGI:2684861
• interleukin 1 receptor, type I
  http://metadb.riken.jp/db/mgi_rdf/MGI:96545

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Il1r1<tm1Roml>/Il1r1<tm1Roml>,Nlrp1a<Neut1>/Nlrp1a<Neut1>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Nlrp1a<Neut1>|Il1r1<tm1Roml>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased platelet cell number
  http://purl.obolibrary.org/obo/MP_0003179

文献

http://purl.org/net/cito/citesAsAuthority

• Seth L. Masters, et.al., NLRP1 inflammasome activation induces pyroptosis of hematopoietic progenitor cells., Immunity, 2012, 37
  http://rdf.ncbi.nlm.nih.gov/pubmed/23219391