thrombocytopenia_Runx1<tm1Soga>/Runx1<tm1.1Soga>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0003179IC57BL6CBARunx1tm1SogaRunx1tm11SogaTgMx1cre1Cgn0Runx1tm11SogaTgMx1cre1CgnRunx1tm1Soga

thrombocytopenia_Runx1<tm1Soga>/Runx1<tm1.1Soga>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• runt related transcription factor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:99852
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Runx1<tm1Soga>/Runx1<tm1.1Soga>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Runx1<tm1.1Soga>|Tg(Mx1-cre)1Cgn|Runx1<tm1Soga>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased platelet cell number
  http://purl.obolibrary.org/obo/MP_0003179

文献

http://purl.org/net/cito/citesAsAuthority

• Motoshi. Ichikawa, et.al., AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis., Nature medicine, 2004, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/14966519