decreased cholesterol efflux_Abca1<tm1Jdm>/Abca1<tm1Jdm>,Abcg1<tm1Dgen>/Abcg1<tm1Dgen>

http://metadb.riken.jp/0003193I129P2OlaHsdC57BL6DBA1LacJAbca1tm1JdmAbca1tm1JdmAbcg1tm1DgenAbcg1tm1DgenAbca1tm1JdmAbcg1tm1Dgen

decreased cholesterol efflux_Abca1<tm1Jdm>/Abca1<tm1Jdm>,Abcg1<tm1Dgen>/Abcg1<tm1Dgen>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• ATP-binding cassette, sub-family A (ABC1), member 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:99607
• ATP-binding cassette, sub-family G (WHITE), member 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:107704

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Abca1<tm1Jdm>/Abca1<tm1Jdm>,Abcg1<tm1Dgen>/Abcg1<tm1Dgen>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Abca1<tm1Jdm>|Abcg1<tm1Dgen>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * DBA/1LacJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased cholesterol efflux
  http://purl.obolibrary.org/obo/MP_0003193

文献

http://purl.org/net/cito/citesAsAuthority

• Laurent. Yvan-Charvet, et.al., Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice., The Journal of clinical investigation, 2007, 117
  http://rdf.ncbi.nlm.nih.gov/pubmed/17992262